Cardiovascular Effects of Griseofulvin

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Cardiovascular effects of griseofulvin.

The intravenous administration of griseofulvin in doses of 3.0 mg/kg to 32 anesthetized open-chest dogs produced marked increments (43%) in isometric systolic force measured by a strain gauge. These changes were accompanied by an increase (22%) in heart rate and a decrease (25%) in blood pressure. The effect was unaltered by clamping the blood supply to and from the adrenal glands or by previou...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1968

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.22.5.589